Reduce Pain and Improve Knee Health Without Surgery
Living with knee issues like osteoarthritis, meniscus tear, or ACL tears can turn daily activities into painful challenges. Whether you experience stiffness in the morning, swelling after activity, or sharp pain with movement, knee pain can significantly impact your quality of life. Surgery is sometimes presented as the only solution, but there are less invasive options that target the underlying causes of knee pain without the risks of surgery.
Why Choose Regenexx?
The Regenexx approach uses your body’s natural healing abilities to help treat knee damage.
- Reduce pain and improve function without surgery.
- Limit the need for prescription medications, frequent office visits, or invasive surgical techniques.
- Minimize downtime from work and activities.
- Concentrations of your own cells are customized for your specific type of knee condition or injury.
- Procedures are performed by board-certified physicians.
Connect with our team for more Regenexx information or to schedule an appointment.
Condensed Candidate Form
Conventional Treatments May Offer Temporary Relief, Not a Long-Term Solution
For knee issues like osteoarthritis, meniscus tears, or ACL tears common treatments like physical therapy, anti-inflammatory medications, and corticosteroid injections may offer temporary relief by reducing pain and inflammation. Unfortunately, these approaches often do not address the root causes of the pain, which means pain may persist or even worsen over time if underlying tissue or joint issues remain untreated. When conservative care or common treatments no longer offer enough relief, surgery is often suggested.
Yet, options like knee replacement or meniscus or ACL repair come with challenges, including a lengthy recovery period, limited knee mobility, and the possibility of complications like infection or blood clots. While surgery can reduce pain, it may not fully restore joint function. After knee surgery, some people may experience changes in the joint over time including stiffness or other functional issues that may require further treatment or additional surgery.
Fortunately, there are alternative treatments that reduce the need for surgery.
Knee Procedure Outcomes
Our patient registry contains real-world data that helps us monitor results and continuously improve patient care. Review our outcomes database to see how many procedures we’re currently tracking and what patients are reporting about their results.
Industry-Leading Musculoskeletal Specialists – Focused on Results
Regenexx patients benefit from the expertise of a board-certified physician who handles both their evaluation and their Regenexx procedure. Patients receive a treatment plan customized to their specific condition or injury needs. Regenexx non-surgical procedures are informed by research, utilize leading biotechnology, and are supported by over 19 years of patient results. These injection-based procedures require less downtime compared to surgery. Regenexx patients return to normal daily activities as tolerated. Most resume light activities and work after 5 to 7 days and return to sports at 6 to 8 weeks.
Doctors
Welcome to the premier destination for interventional and regenerative pain management in the Chicago area. Led by Dr. Nicholas Angelopoulos, a highly respected physician with over 30 years of experience, our practice is dedicated to helping patients overcome pain and restore their quality of life.
Dr. Angelopoulos is board-certified in interventional pain management and anesthesiology. He trained at the renowned University of Chicago, bringing world-class expertise coupled with compassion to every patient interaction. Specializing in the treatment of spinal and orthopedic injuries, we combine proven interventional techniques with cutting-edge regenerative therapies to deliver lasting relief with improved mobility and function.
Our advanced treatment options include, but are not limited to:
- Bone Marrow Concentrate which contains stem cells: Harnessing your body’s natural ability to heal.
- Platelet-Rich Plasma (PRP) Therapy: Stimulating recovery through concentrated growth factors.
With a commitment to patient-centered care, Dr. Angelopoulos and his team take the time to understand each patient’s unique challenges and goals. Whether managing chronic pain or addressing acute injuries, we aim to provide compassionate care tailored to your needs.
Outside of his work, Dr. Angelopoulos is an avid Chicago sports fan and enjoys cheering on his favorite teams, especially the Chicago Bears. He is also passionate about traveling with his family, exploring new places, and connecting with diverse cultures. When he’s not helping patients or on the road, you might find him tending to his garden, where he finds joy and relaxation in nurturing vibrant plants, flowers, and heirloom tomatoes.
Discover how our innovative solutions and personalized approach can help you move past pain and get back to doing what you love.
Areas treated: Cervical Spine (Not Upper Cervical or CCI)*, Thoracic Spine, Lumbar Spine, Hip, Knee
Clinic Locations
Integrity Interventional Pain and Regenerative Medicine - Hinsdale
908 North Elm Street
#301
Hinsdale, IL 60521
Phone: 708-429-3466
Hours:
- Fri-Sun: Closed
- Mon-Thu: 8:30AM–3:30PM
Integrity Interventional Pain and Regenerative Medicine - Tinley Park
6850 W Centennial Drive
Tinley Park, IL 60477
Phone: 708-429-3466
Hours:
- Fri-Sun: Closed
- Mon-Thu: 8:30AM–3:30PM

- Wrist
- Hand
- Elbow
- Shoulder
- Neck
- Middle Back
- Low Back
- Hip
- Knee
- Ankle
- Foot
Commonly Treated Orthopedic Conditions
Regenexx procedures may help you avoid orthopedic surgeries, reduce pain, and improve joint function. Regenexx highly-skilled physicians treat a variety of orthopedic issues.
Select a body area in the adjacent image to see their common conditions.
Commonly Treated Orthopedic Conditions
Regenexx procedures may help you avoid orthopedic surgeries, reduce pain, and improve joint function. Regenexx highly-skilled physicians treat a variety of orthopedic issues.
Select a body area in the adjacent image to see their common conditions.